Induced with antigens h37rv and esat-6 production interferon-г whole blood of the patients pulmonary tuberculosis

  • Т. Ю. Салина Medical university, Saratov,
  • М. А. Владимирский Medical university, Saratov,
  • Т. И. Морозова Research institute of Phthisiopulmonology, Sechenows Moscow Medical Academy
Keywords: tuberculosis, gamma interferon, pontaneous and induced production, whole peripheral blood

Abstract

We studied the spontaneous and induced H37Rv and ESAT-6 production IFN-y in supernatants 48 hours cultures whole blood of the patients with active pulmonary tuberculosis (n=36). It was found decreasing induced production IFN-y of the patients with high-gravity progressing flow of tuberculosis (group 2) in response to H37Rv 10,9±3,8 pg/ml and ESAT-6 24,8±9,3 pg/ml against 225,4±102,0 pg/ml and 65,0±15,0 pg/ml accordingly (p<0,05) for the patients (group 1) with favourable flow of tuberculosis process. Thus, offer method can be useful for appraisement gravity course tuberculosis.
Published
2018-05-31
How to Cite
Салина, Т., Владимирский, М., & Морозова, Т. (2018). Induced with antigens h37rv and esat-6 production interferon-г whole blood of the patients pulmonary tuberculosis. Bulletin of the International Scientific Surgical Association, 1(2), 56-57. Retrieved from http://surgjournal.ru/index.php/BISSA/article/view/94
Section
Original Articles