Research in vitro influence degree of venous valvular stenosis on dynamics of fluid flow

  • О. А. Кудрявцева I.M. Sechenov Moscow Medical Academy, Moscow, Russia
Keywords: vein, in vitro, artificial venous valve, stenosis, volume rate flow


A significant number new patents design of artificial venous valves (AVV) need for comparison studies. Purpose of this study was to investigate in vitro influence degree of stenosis as the result of AVV on dynamics offluid flow. Mod¬els of AVV manufactured from polymer were subjects of this study. Each model of AVV was having definite outflow cross-sectional area been examined. For different antegrate pressure was determined volume rate flow and fluid resistance in the cases with and without models of AVV. Degree of venous valvular stenosis is significance factor which have influence on fluid resistance, below 70% degree of venous valvular stenosis fluid resistance rises slowly, in the range 70 - 85 % has essential increase value and over 85 % was noted sharp rise of fluid resistance . Keywords:


А.В.Гавриленко, Ф.А.Радкевич «Новые возможности лече¬ния клапанной недостаточности глубоких вен» Вестник трансплантологии и искусственных органов №1, 2004, 61¬70

S.E.Rittgers, M.T.Oberdier, S.Pottala “Physiologically-based testing system for the mechanical characterization of prosthetic vein valves” Biomedical Engineering OnLine, 13 July 2007, 1¬12)

M.Siebes, S.A.J. Chamuleau, M.Meuwissen, J.J.Piek, J.A.E.Spaan “Influence of hemodynamic conditions on frac¬tional flow reserve: parametric analysis of underlying model” Am J Physiol Heart Circ Physiol 283: H1462-H1470, 2002.

J.J.McCaughan, D.B.Walsh, L.P.Edgcomb, H.E.Garrett “In vitro observations of greater saphenous vein valves during pulsatile and nonpulsatile flow and following lysis” J Vasc Surg 1984; 1: 356-61

F. Lurie, R. L. Kistner, Bo Eklof and Darsy Kessler “The mechanism of venous valve clouse and role of the valve in circulation: A new concept.” J Vasc Surg 2003; 38: 955-61.

How to Cite
Кудрявцева, О. (2007). Research in vitro influence degree of venous valvular stenosis on dynamics of fluid flow. Bulletin of the International Scientific Surgical Association, 2(2-3), 70-71. Retrieved from
Original Articles